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WHAT IS THIS ?

Zero Exosome Shot – Exceptional Care for Regenerated Skin

Discover the experience of a true skin transformation.

The Zero Exosome Shot is an advanced technology ampoule, inspired by microneedling, formulated with a micro-sized, needle-like booster for deep, targeted action.

Thanks to its 15 million patented exosomes , this innovative formula delivers active ingredients directly to the heart of the pores, offering intensive daily treatment at home, worthy of professional protocols.

Clinically proven, it visibly reduces pore size, refines skin texture, strengthens the skin barrier and brightens the complexion.

Upon application, a slight tingling sensation may be felt, a sign of the active action of the powerful ingredients, designed to reactivate your skin's natural radiance.

Non-comedogenic

Dermatologically tested for low irritation

Gluten-free

No artificial coloring

Capacity : 30 ml / 1.01 fl. oz.

MAIN INGREDIENT

Cutting-Edge Technology for Regenerated Skin

Exosome-coated spicules (Hydrolyzed Sponge)

Natural microneedles gently penetrate the epidermis to deliver next-generation skincare. Far beyond traditional formulations, Exosome Shot incorporates exosome-coated spicules for targeted delivery and deep skin revitalization.

Lacto Exosome – Medicube’s Signature Active

The result of patented technology, this exosome enriched with peptides, amino acids, glutathione and vitamins regenerates damaged tissue, restores vitality and strength to the skin, and effectively treats daily skin concerns to reveal healthy, radiant skin.

AHA + BHA + PHA complex

A trio of high-performance acids that gently exfoliate, remove dead cells and stimulate cell renewal for visibly smoother and brighter skin.

Niacinamide

A powerful shield that strengthens the skin barrier and intensely hydrates for plump, radiant skin.

Panthenol

A soothing and restorative active ingredient, it restores skin hydration and contributes to a softer, more supple texture.

HOW TO USE IT

Instructions for Use

Beginners

After cleansing your skin, apply a hydrating toner like Zero Pore Pads .

Target the areas to be treated with the Zero One Day Exosome Shot , massage and pat to promote absorption.

Finish with Collagen Jelly Cream or your usual light moisturizer.

Standard Use

After cleansing, apply Zero One Day Exosome Shot directly to your entire face, avoiding the eye and lip area.

Gently massage in the micro-needle formula, then follow with a water-based moisturizer.

Tip: Maximize results by combining the Exosome Shot with the Air Shot mode of the AGE-R Booster Pro .

Important Tips

Avoid the sensitive eye and lip area.

For sensitive skin, perform a skin test first.

A slight tingling sensation is normal, a sign of the active action of exosomes.

FAQ

Q. Is it normal to feel tingling after application?

The Exosome Shot Ampoule contains microparticles of natural origin, which may cause a tingling sensation upon application.

This is a normal reaction related to the active diffusion of ingredients into the pores.

We recommend adjusting the amount and frequency of use based on your skin's sensitivity.

Q. Are there any ingredients to avoid in combination?

There are no ingredients that are specifically contraindicated. However, for sensitive skin, certain combinations may cause irritation or hypersensitivity reactions.

A skin test is recommended, as well as gradual adjustment of the amount and frequency of use.

Q. I want to specifically target my pores. Are there any complementary products?

Used in synergy with the One-day Serum and the One-day Cream , the Exosome Shot allows an 88% improvement in pore volume and 85% in their surface area, compared to use alone.

For optimal pore care, first apply the Exosome Shot Ampoule , follow with the One-day Serum , then finish with the One-day Cream .

Excerpt from in vivo skin absorption tests. Results may vary depending on the individual.

CUSTOMER REVIEWS

★★★★★ Aurora L.

I love it, I love it, I love it!!!

It was—and still is—great! I use it twice a week, and my skin feels fresh and renewed after each use.

★★★★★ Stefanny T. – Light to very light, combination skin, 26-35 years old, concerns: pores and blackheads

Best buy. My skin stays soft and clean.

★★★★★ Paula – Fair to very fair, combination skin, 36-45 years old, concerns: pores, spots, uneven skin tone

I was skeptical, but now I'm convinced.

After just a few uses, I noticed a real difference. I recommend it!

★★★★★ Driks – Fair to very fair skin, normal, 18-25 years old, concerns: acne

I love it. It stings, but the results are there!

★★★★★ Sidh – Medium to dark, combination to normal skin, 36-45 years old, concerns: pores, spots, signs of aging, dryness, redness

An incredible purchase, super effective for beginners.

★★★★★ Jen – Fair to very fair, combination skin, 26-35 years old, concerns: pores, signs of aging

I adore.

I even used it on my scalp and noticed new hair growth. I will continue.

★★★★★ Sidh

This set is amazing and really plumps the skin from the first use.

I highly recommend starting with this set if you are new to Medicube.

★★★★★ Yeisy Q. – Fair to very fair, combination skin, 36-45 years old, concerns: pores, spots, signs of aging, dryness

Unique experience.

A way to take your skincare routine to the next level. Totally seduced.

★★★★★ Tippy – Medium to dark, oily skin, ages 36-45, concerns: pores, acne, spots

I adore.

Having acne-prone and scar-prone skin, this product has become a must-have despite the slight tingling sensation. Impressive results!

★★★★★ Kim C. – Medium to dark, dry to normal skin, 46-55 years old, concerns: spots, signs of aging, dryness

I own many Medicube products.

My overall experience is excellent.

★★★★★ Monica – SVG verified by SHOP

I love Medicube products, they are definitely worth the investment!

★★★★★ Monica – SVG verified by SHOP

This product is amazing.

The results are visible and noticeable almost immediately!

★★★★★ Regine G. – Medium to dark, normal skin, 36-45 years old, concerns: pores and blackheads

I adore.

Really helps visibly reduce pores.

★★★★★ Waren S. – Medium to dark, combination skin, 46-55 years old, concerns: pores, acne, spots

I highly recommend.

This is my first bottle and I'm already seeing results. I've ordered two more!

★★★★★ Sofia C. – Light to very light skin, dry, 26-35 years old, concerns: acne, spots

Awesome.
I love it and will continue to buy.

97% of users report smoother, brighter, and visibly transformed skin after just one application. Based on verified customer reviews and results observed with regular use.

4.5
Rated 4.5 out of 5 stars
Basé sur 59 avis
Total des avis 5 étoile(s) : 27 Total des avis 4 étoile(s) : 32 Total des avis 3 étoile(s) : 0 Total des avis 2 étoile(s) : 0 Total des avis 1 étoile(s) : 0
100%recommanderaient ce produit
59 avis
  • Z
    Zoé
    Drapeau de France
    Acheteur vérifié
    Je recommande ce produit
    Rated 5 out of 5 stars
    il y a 5 mois
    Medicube One Day Exosome Shot Pore Ampoule 2000 30Ml

    Excellente composition et résultats impressionnants.

  • A
    Aya
    Drapeau de France
    Acheteur vérifié
    Je recommande ce produit
    Rated 4 out of 5 stars
    il y a 6 mois
    Medicube One Day Exosome Shot Pore Ampoule 2000 30Ml

    J’adore ! C'est exactement ce dont j'avais besoin.

  • I
    Inès
    Drapeau de France
    Acheteur vérifié
    Je recommande ce produit
    Rated 4 out of 5 stars
    il y a 6 mois
    Medicube One Day Exosome Shot Pore Ampoule 2000 30Ml

    Ce produit a changé ma routine ! Résultats visibles en quelques jours.

  • Y
    Yasmine
    Drapeau de France
    Acheteur vérifié
    Je recommande ce produit
    Rated 5 out of 5 stars
    il y a 6 mois
    Medicube One Day Exosome Shot Pore Ampoule 2000 30Ml

    Très efficace, conforme à la description et agréable à utiliser.

  • L
    Louise
    Drapeau de France
    Acheteur vérifié
    Je recommande ce produit
    Rated 5 out of 5 stars
    il y a 6 mois
    Medicube One Day Exosome Shot Pore Ampoule 2000 30Ml

    Je suis agréablement surpris(e) par ce produit. Belle découverte !

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DISCOVER THE MEDICUBE BRAND

Medicube, dermatological expertise at the service of your skin.
Medicube places skin concerns at the heart of its mission. The brand develops innovative solutions through continuous research, rigorous selection of active ingredients, and formulas tested for their effectiveness. Each product is designed to meet the real needs of the skin and deliver visible and lasting results .
Targeted care, clearer skin, restored confidence.

Discover the Medicube difference